FROM MIT NEWS Research update: Continuous medical monitoring Tiny 'microworms' could be implanted under the skin to give readout of blood sugar levels or other biomedical information. Researchers at MIT and Northeastern have come up with a new system for monitoring biomedical indicators — such as levels of sodium or glucose in the blood — that could someday lead to implantable devices that would allow, for example, people with diabetes to check their blood sugar just by glancing at an area of skin. A number of researchers have developed microparticle-based systems — hollow, microscopic particles filled with specific chemicals — for monitoring biomedical conditions or for the selective delivery of drugs to certain organs or areas of the body. But one drawback of these systems is that the particles are small enough to be swept away from the initial site over time. The new system involves a different kind of microparticle that can avoid this problem. While traditional particles are spherical, the new particles are shaped like long tubes. The tubes’ narrow width, which is comparable to that of the previously studied microparticles, keeps the tubes’ contents in close proximity to blood or body tissue, making it easy for the particles to sense and respond to chemical or other conditions in their surroundings. The tubes’ relatively greater length keeps the tubes very well anchored in place for long-term monitoring, perhaps for months on end. The particles eventually could be used to monitor the glucose levels of diabetics or the salt levels of those with a condition that can cause swings in blood salt concentrations. The new findings are being reported in the journal Proceedings of the National Academy of Sciences, in a paper published online in January and soon to appear in the print version. It was co-authored by Karen Gleason, the Alexander and I. Michael Kasser Professor of Chemical Engineering at MIT; Heather Clark, professor of pharmaceutical science at Northeastern University; MIT postdoctoral researcher Gozde Ozaydin-Ince; and Northeastern doctoral student J. Matthew Dubach. The process of creating the new nanoparticles is an offshoot of Gleason’s work on a method of coating materials by vaporizing the coating material and letting it deposit on a surface to be coated. In work published last month, she and her co-workers had shown that this technique — called chemical vapor deposition (CVD) — could be used to coat a material containing microscopic pores, thus making the pores even smaller and giving them a surface that could respond to the chemical properties of materials passing through them. READ MORE Add Comment Why food matters (documentary 2010) 12/25/2010
A "New" Approach to Health from Jamie Simko on Vimeo. FROM FAST COMPANY 500 Million People to Use Mobile Health Apps by 2015: mHealth Study Five hundred million people will be using mobile health apps by 2015, according to the "Global Mobile Health Market Report 2010-2015," released yesterday. "Our findings indicate that the long-expected mobile revolution in healthcare is set to happen. Both healthcare providers and consumers are embracing smartphones as a means to improving healthcare," said head researcher, Ralf-Gordon Jahns. The study was part of the mHealth Summit, which wrapped Wednesday and offered a picture on industry that's booming at home and abroad. Of the current health apps on the market, 43% are designed for health care professionals, indicating the future of mHealth has far-reaching personal and institutional potential. Bill Gates keynoted the conference and was clear about the future or mobile health. "Diagnosis of malaria and TB will likely be the first ones you can assign a number to and say without this mobile phone app these people would have died," Gates said. "In the diagnostics areas we're seeing some very good stuff come through." On the domestic front, Jeffrey Shuren, director of the FDA's Center for Devices and Radiological Health, said, “We need to be moving towards open sourced, independent infrastructure where you have components of different manufacturers that can plug and play. FDA is looking to the development of those different types of standards to get the biggest bang for our buck.” READ MORE Poor people just need to be happier to close health gap between rich and poor claims Zcience 10/26/2010
Peace of Mind Closes Health Gap for Less-Educated, Study Finds ScienceDaily (Oct. 25, 2010) — Psychological well-being is powerful enough to counteract the pull of socioeconomic status on the long-term health of the disadvantaged, according to a study by researchers at the University of Wisconsin-Madison. Lack of education is a powerful predictor of future poor health and a relatively early death. But among people whose formal education ended with a high school diploma or less, positive psychological characteristics such as meaningful relationships with others and a sense of purpose have a strong connection with lower levels of an inflammatory protein connected to an array of potentially deadly health problems. "If you didn't go that far in your education, but you walk around feeling good psychological stuff, you may not be more likely to suffer ill-health than people with a lot of schooling," says Carol Ryff, UW-Madison psychology professor and co-author of the study, which appears in the current online edition of the journal Health Psychology."Low educational attainment does not guarantee bad health consequences, or poor biological regulation." The researchers measured levels of Interleukin-6 in participants in the Survey of Midlife in the United States, a now 10-year-long study of age-related differences in physical and mental health. "High levels of IL-6 are associated with many kinds of cardiovascular disease, stroke, diabetes, metabolic syndrome, some cancers and other health problems," says Jennifer Morozink, a UW-Madison psychology graduate student and lead author of the study. "These positive psychological characteristics all moderate the level of IL-6 for people without much education." Less-educated people who scored high on measures of general happiness or self-acceptance or who felt that the circumstances of their lives were manageable showed levels of the inflammatory protein comparable to similarly satisfied, but highly-educated peers. The results are significant, according to Ryff, because they reinforce a new angle on eliminating the wide gap in overall health between the well-to-do and the socioeconomically disadvantaged. "Other research shows that these psychological factors respond well to intervention," Ryff says. "Therapies exist that give people the tools to keep all these psychological characteristics working in their favor. They've been shown to keep people from falling back into depression and anxiety, which we know means bad things for their health." READ MORE FROM NEW SCIENTIST Universal flu vaccine one step closer Feeling stuffy and miserable? Forgot your flu jab this year? What you need is a vaccine that will stop flu once and for all – and prospects for one have just got brighter. A protein touted as flu's Achilles' heel when it was discovered last year has now been tested as a vaccine, and it worked, at least partially, against every version of human flu. People need to be vaccinated against flu every year. This is because the flu virus is a scam artist: it uses a big, showy surface protein to attract your immune system, then changes it so your immune system won't recognise it next time round. Vaccines must change yearly to match it. Worse, there are 16 different varieties of this protein, called Hemagglutinin (HA), and immunity to one doesn't work on the others. Pandemics happen when flu swaps one for another, as swine flu did last year. If we could identify a flu protein that the virus can't alter so readily, then we should be able to elicit immunity that recognises all kinds of flu. Mushroom stalkLast year, two groups reported a promising candidate: part of the stalk of the mushroom-shaped HA, a vital bit of viral machinery which doesn't vary much over time or between viruses. One of those groups, at Scripps Research Institute in la Jolla, California, teamed up with Peter Palese and colleagues at Mount Sinai Medical School in New York to test that protein as a vaccine. They report that 54 amino acids from this bit of the stalk, linked to a protein that attracts immune reactions, induced antibodies that work against viruses from every flu family that attacks people. These included three pandemic viruses (H1, H2 and H3), three others that attack occasionally (H6, H9 and H7), and the H5N1 bird flu from 2004 – albeit modified to make it less deadly. Mice were injected with this protein twice, three weeks apart, to allow their immunity to develop. Two weeks after the second injection each mouse was exposed to one type of live flu virus, as were unvaccinated mice. The team found that doses of the viruses that killed unvaccinated mice did not kill any vaccinated mice – except for the H5N1 virus, and then more than half the vaccinated mice survived. Vaccinated mice still became ill, but not as ill as unvaccinated mice, judging from the weight they lost, a standard measure of illness in mice. READ MORE Carcinogenic CT scans? 09/26/2010
Lethal Danger of CT Scans By William FaloonWilliam FaloonWe tried everything… from pleading with arrogant physicians to providing irrefutable documentation to support our position. The response was always the same: we were “out of our minds” for suggesting that medical X-rays increase future cancer risks. Our opposition could never substantiate that exposing healthy cells to ionizing radiation was safe. They did at one point rely on theAtomic Energy Commission, who claimed there were no dangers to low-level radiation exposure. The Atomic Energy Commission was created to “manage the development, use, and control of atomic (nuclear) energy for military and civilian applications.” Like so many federal agencies, the priority was not to protect the public’s health. Instead this tax-funded bureaucracy (like the FDA) functioned to guarantee the economic success of the industries it regulated.1 By ridiculing those who warned about the carcinogenic effects of X-rays, the federal government and medical establishment enabled companies making CT scanners (and other radiation devices) to earn tens of billions of dollars in profit, with Medicare and private health insurance picking up most of the costs. Radiation OverloadCompared to regular medical X-rays, CT scans yield much higher-resolution images. Unfortunately, CT scans also expose the patient to hundreds and sometimes thousands of times more radiation.2-4 The routine use of CT scans and other dangerous X-ray imaging procedures has skyrocketed over the past three decades. In 1980, there were 3 million CT scans done. By the year 2007, the number increased to about 70 million.5,6 We at Life Extension® long ago warned members to avoid CT scans and any kind of X-ray unless absolutely necessary. Up against us was an armada of for-profit companies who promoted CT scans to healthy people to measure coronary artery calcification, virtual colonoscopy in place of the more effective standard colonoscopy (flexible tube procedures), and even whole-body CT scans to identify abnormalities anywhere in one’s anatomy. The irony is that health-conscious people, who often paid for whole-body CT scans out of their own pockets, unwittingly exposed their whole body to huge levels of DNA gene-mutating radiation! Absolutely Shocking DataThe uninformed public is in for a shocker. A study released at the end of last year reveals that CT scans deliver up to four times more radiation than what was previously believed, which was already dangerously high.7 At the same time, another study led by the National Cancer Institute showed that CT scans administered in the year 2007 alone may contribute to 29,000 new cancer cases and nearly 15,000 cancer deaths.8 The problem is that the explosion in unnecessary CT scans has been going on every year. If we carry this back just ten years, this means that 150,000 Americans are facing horrific deaths from CT scan-induced cancers. READ MORE Wifi sickness and electromagnetic radiation 08/17/2010
FROM ECANADA NOW Barrie Parrents Say Wi-Fi Can Make You SickPosted by Staff on Aug 17th, 2010 // No Comment Can Wi-Fi Make You Sick? Wireless Internet has become vastly popular, with networks appearing in restaurants, schools, and shopping malls. But new speculation has risen that says Wi-Fi may be making some people sick. Some in the scientific community suggest that electromagnetic radiation released from wireless routers could have a negative effect on health. That has lead to an outcry from parents who are against adding wireless networks to schools until further research is conducted. Last fall, parents in Barrie, Ontario had a failed attempt to ban Wi-Fi from schools because of health reasons. Now, the Ontario Education Minister is requesting information regarding the potential health concerns. The debate is at a height again, with parents, teachers, and administrators all wanting more information. Those in the scientific community are also debating the issue. While they agree that radiation is released, the debate centers on the amounts. Some say it is negligible and would fall well within the guidelines of various national health administrations. Others say that Wi-Fi has been known to cause health issues such as nausea and headaches. The World Health Organization says that Wi-Fi is safe as long as it falls under the exposure limits. Despite the findings by the World Health Organization and other scientific bodies, the debate over the potential risks of Wi-Fi is stirring the debate among the schools. While the parents in Barrie continue to demand the elimination of Wi-Fi, the school board has yet to do so. They are saying there isn’t sufficient evidence to warrant removing wireless networks from the schools. The issue in Barrie isn’t new. As far back as 2006, the safety of Wi-Fi has been called in to question. Lakewood University in Ontario banned campus wide Wi-Fi that year, and other schools have followed suit. The fears over Wi-Fi are likely to spark further research on the issue. READ MORE Smart pill texts - time for your medicine Volunteers are being recruited to take standard versions of their heart pill fitted with a microchip. When swallowed, the chip send signals to a patch attached to the patient's shoulder. The patch can also send a text if the patient forgets to take the medication. The system, known as Raisin, also monitors heart activity and how well the patient is sleeping all of which may signal a deteriorating condition. It costs a few cents per pill and was initially tested in the US, where it lifted patients' consistency in taking their medication from 30 per cent to 80 per cent. If successful, the four-month test could lead to a year-long trial by Britain's health service. Nicholas Peters, professor of cardiology at Imperial College Healthcare, said the main aim was to get heart patients to stick to taking their pills. "It will encourage patients to take responsibility for their own health," he said. With a stricter medication regimen, it is hoped their health will improve and they will be less likely to be admitted to hospital in an emergency. The chips, developed by California-based company Proteus Biomedical, are tiny, digestible sensors made from food ingredients. Read more: http://www.news.com.au/technology/smart-pill-texts-time-for-your-medicine/story-e6frfro0-1225905939359#ixzz0wkqCudDp From The Gaurdian Insects could be the key to meeting food needs of growing global population The UN Food and Agriculture Organisation is taking seriously the farming of creepy-crawlies as nutritious food Saving the planet one plateful at a time does not mean cutting back on meat, according to new research: the trick may be to switch our diet to insects and other creepy-crawlies. The raising of livestock such as cows, pigs and sheep occupies two-thirds of the world's farmland and generates 20% of all the greenhouse gases driving global warming. As a result, the United Nations and senior figures want to reduce the amount of meat we eat and the search is on for alternatives. A policy paper on the eating of insects is being formally considered by the UN Food and Agriculture Organisation. The FAO held a meeting on the theme in Thailand in 2008 and there are plans for a world congress in 2013. Professor Arnold van Huis, an entomologist at Wageningen University in the Netherlands and the author of the UN paper, says eating insects has advantages. "There is a meat crisis," he said. "The world population will grow from six billion now to nine billion by 2050 and we know people are consuming more meat. Twenty years ago the average was 20kg, it is now 50kg, and will be 80kg in 20 years. If we continue like this we will need another Earth." Van Huis is an enthusiast for eating insects but given his role as a consultant to the FAO, he can't be dismissed as a crank. "Most of the world already eats insects," he points out. "It is only in the western world that we don't. Psychologically we have a problem with it. I don't know why, as we eat shrimps, which are very comparable." The advantages of this diet include insects' high levels of protein, vitamin and mineral content. Van Huis's latest research, conducted with colleague Dennis Oonincx, shows that farming insects produces far less greenhouse gas than livestock. Breeding commonly eaten insects such as locusts, crickets and meal worms, emits 10 times less methane than livestock. The insects also produce 300 times less nitrous oxide, also a warming gas, and much less ammonia, a pollutant produced by pig and poultry farming. Being cold-blooded, insects convert plant matter into protein extremely efficiently, Van Huis says. In addition, he argues, the health risks are lower. He acknowledges that in the west eating insects is a hard sell: "It is very important how you prepare them, you have to do it very nicely, to overcome the yuk factor." More than 1,000 insects are known to be eaten by choice around the world, in 80% of nations. They are most popular in the tropics, where they grow to large sizes and are easy to harvest. The FAO's field officer Patrick Durst, based in Bangkok, Thailand, ran the 2008 conference. Durst helped set up an insect farming project FAO project in Laos which began in April. This involves transferring the skills of the 15,000 household locust farmers in Thailand across the border. "There were some proponents of a bigger dairy industry in Laos to improve a calcium deficiency," says Durst, whose favourite is fried wasp - "very crispy and a nice light snack". "But this is crazy when most Asians are lactose intolerant." Locusts and crickets are calcium-rich and 90% of people in Laos have eaten insects at some point, he says.Durst says the FAO's priority will be to boost the eating of insects where this is already accepted but has been in decline due to western cultural influence. He also thinks such a boost can provide livelihoods and protect forests where many wild insects are collected. "I can see a step-by-step process to wider implementation." First, insects could be used to feed farmed animals such as chicken and fish which eat them naturally. Then, they could be used as ingredients. Van Huis adds: "We're looking at ways of grinding the meat into some sort of patty, which would be more recognisable to western palates." One of the few suppliers of insects for human consumption in the UK is Paul Cook, whose business Osgrow is based in Bristol. However, no matter how they are marketed or presented, Cook is not convinced they will ever become more than a novelty. "They are in the fun element ... But I can't see it ever catching on in the UK in a big way." • This article was amended on 2 August 2010. In the original, Professor Arnold van Huis was described as an entomologist at Wageningen University in Belgium. This has been corrected. READ MORE FROM: U of Fl. GAINESVILLE, Fla. — Call them tattletale pills. Seeking a way to confirm that patients have taken their medication, University of Florida engineering researchers have added a tiny microchip and digestible antenna to a standard pill capsule. The prototype is intended to pave the way for mass-produced pills that, when ingested, automatically alert doctors, loved ones or scientists working with patients in clinical drug trials. “It is a way to monitor whether your patient is taking their medication in a timely manner,” said Rizwan Bashirullah, UF assistant professor in electrical and computer engineering. Such a pill is needed because many patients forget, refuse or bungle the job of taking their medication. This causes or exacerbates medical problems, spurs hospitalizations or expensive medical procedures and undercuts clinical trials of new drugs. The American Heart Association calls patients’ failure to follow prescription regimens “the number one problem in treating illness today.” Studies have found, for example, that patients with chronic diseases normally take only about half their prescribed medications. According to the American Heart Association, 10 percent of hospital admissions result from patients not following the guidelines on their prescriptions. Other studies have found that not taking medication properly results in 218,000 deaths annually. READ MORE | All News
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